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The solvent was then evaporated and the crude material was purified using preparative HPLC to afford the desired compound. Which one of the following grades indicates that a recommendation is based on consistent, good-quality, patient-oriented evidence? The crude product was purified by preparative liquid chromatography using a C 18 stationary phase with eluent A: 0.1% TFA in water and eluent B: 0.1% TFA in acetonitrile.

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